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Histochemistry

, Volume 80, Issue 5, pp 435–441 | Cite as

Ultrastructural localization of secretin in endocrine cells of the dog duodenum by the immunogold technique

Comparison with ultrastructurally characterized S cells of various mammals
  • L. Usellini
  • C. Capella
  • B. Frigerio
  • G. Rindi
  • E. Solcia
Article

Summary

Secretin has been localized by the immunogold technique in endocrine cells of the dog duodenum — previously described as “K cells” — characterized by secretory granules with double structure consisting of a secretin-containing osmiophilic core surrounded by an argyrophil halo. Granules resembling those of dog secretin cells were also found in some ultrastructurally characterized S cells of the cat, pig, rat and rabbit duodenum, thus confirming in these species the identification of S cells with secretin cells. Conversely, the cells previously described as “S cells” in the dog lacked secretin immunoreactivity.

Keywords

Public Health Secretin Secretory Granule Endocrine Cell Ultrastructural Localization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • L. Usellini
    • 1
    • 2
  • C. Capella
    • 1
    • 2
  • B. Frigerio
    • 1
    • 2
  • G. Rindi
    • 1
    • 2
  • E. Solcia
    • 1
    • 2
  1. 1.Histopathology, Histochemistry and Ultrastructure Research CentreUniversity of Pavia at VaresePaviaItaly
  2. 2.Department of Human PathologyUniversity of PaviaPaviaItaly

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