Summary
A lead-salt procedure was used for the cytochemical demonstration of aspartate aminotransferase (AT) in the CA3 of the rat hippocampus. Cytoplasmic- and mitochondrial-AT isoenzymes were demonstrated in different neuronal structures, but not in astrocytes. Of special interest was the localization of cytoplasmic AT in most mossy-fibre boutons. This might indicate that cytoplasmic AT is responsible for the production of releasable glutamate in the glutamatergic/aspartatergic mossy fibre system.
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Supported by the Deutsche Forschungsgemeinschaft (Ku 541/2-1)
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Kugler, P. Cytochemical demonstration of aspartate aminotransferase in the mossy-fibre system of the rat hippocampus. Histochemistry 87, 623–625 (1987). https://doi.org/10.1007/BF00492481
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DOI: https://doi.org/10.1007/BF00492481