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Studies on a strain of Fusarium solani (Mart.) Sacc. Isolated from a case of mycotic keratitis

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Abstract

A strain of Fusarium solani (Mart.) Sacc. (IMI-216517), isolated from a patient of mycotic keratitis, produced experimental keratomycosis in albino rabbit cornea and survived in internal tissues of albino mice for varying periods. Alantolactone, isolated from the plant — Inula racemosa Hook. f. exhibited marked in vitro fungistatic activity against this strain of F. solani at 100–200 μg/ml concentrations. The strain was less sensitive to amphotericin B and showed more acid than alkaline proteinase and phosphatase activities.

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Authors and Affiliations

  1. Fermentation Technology Division, Central Drug Research Institute, Lucknow, India

    Seema Wahab, Z. Jacob & O. P. Srivastava

  2. Biochemistry Division, Central Drug Research Institute, Lucknow, India

    V. C. Pandey

  3. Ophthalmology Department, King George's Medical College, Lucknow, India

    B. Lal

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  1. Seema Wahab
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  2. B. Lal
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  3. Z. Jacob
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  4. V. C. Pandey
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  5. O. P. Srivastava
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Communication No. 2526.

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Wahab, S., Lal, B., Jacob, Z. et al. Studies on a strain of Fusarium solani (Mart.) Sacc. Isolated from a case of mycotic keratitis. Mycopathologia 68, 31–38 (1979). https://doi.org/10.1007/BF00490388

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