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Histochemistry

, Volume 44, Issue 4, pp 303–306 | Cite as

Electron microscopic observations on the cholesterol distributed in the epithelial cells of the gallbladder

  • Akitoshi Koga
  • Satoru Todo
  • Masaya Nishimura
Article

Summary

Epithelial cells of eight human gallbladders with cholesterosis were examined. In the supranuclear portion of the epithelial cells of one case, many spicular, circular and plate-like pale crystalline structures are present. Spicular and circular structures have not a limiting membrane, but plate-like structures are apparently bounded by a limiting membrane that clearly shows trilamellar structure. After digitonin treatment, the spicular and circular crystalline structures become denser. On the other hand, the plate-like structures do not become denser by digitonization. In the epithelial cells that contain no crystalline structure, there also occur many reaction precipitates after digitonization. These findings may suggest that free cholesterol is highly present in the epithelial cells of gallbladder with cholesterosis and that it, in some case, precipitates in the form of spicular or circular structure for the rapid fixation process.

Keywords

Public Health Cholesterol Epithelial Cell Crystalline Structure Microscopic Observation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • Akitoshi Koga
    • 1
  • Satoru Todo
    • 1
  • Masaya Nishimura
    • 1
  1. 1.1st Department of Surgery, Faculty of MedicineKyushu UniversityFukuokaJapan

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