, Volume 88, Issue 1, pp 31–36 | Cite as

Localization of enkephalin- and neurotensin-like immunoreactivities in cat adrenal medulla

  • M. Pelto-Huikko
  • T. Salminen
  • A. Hervonen


Enkephalin (ENK)- and neurotensin (NT)-immunoreactivities (IR) were localized in cat adrenal medulla using immunocytochemistry. ENK was localized mainly in adrenaline cells, 70%–80% of which were heavily labelled. About 5%–10% of the noradrenaline cells were ENK-immunoreactive (IR). A dense network of ENK-IR nerves was localized among adrenaline cells. NT was localized only in the noradrenaline cells, 60%–70% of which were immunoreactive. NT- and ENK-IR were localized in separate noradrenaline cells. A dense network of NT-IR nerves was restricted among noradrenaline cells.

The present findings confirm that ENK- and NT-like peptides are localized in separate adrenal medullary cells and demonstrate that also the preganglionic nerves are divided in subpopulations according to their neuropeptide content. These nerves have a selective localization among adrenaline and noradrenaline cells and may have physiological significance in the control of secretion of catecholamines and neuropeptides from adrenal medulla.


Public Health Peptide Noradrenaline Adrenaline Catecholamine 
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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • M. Pelto-Huikko
    • 1
  • T. Salminen
    • 1
  • A. Hervonen
    • 2
  1. 1.Department of Biomedical SciencesUniversity of TampereTampereFinland
  2. 2.Department of Public HealthUniversity of TampereTampereFinland

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