Histochemistry

, Volume 88, Issue 1, pp 31–36 | Cite as

Localization of enkephalin- and neurotensin-like immunoreactivities in cat adrenal medulla

  • M. Pelto-Huikko
  • T. Salminen
  • A. Hervonen
Article

Summary

Enkephalin (ENK)- and neurotensin (NT)-immunoreactivities (IR) were localized in cat adrenal medulla using immunocytochemistry. ENK was localized mainly in adrenaline cells, 70%–80% of which were heavily labelled. About 5%–10% of the noradrenaline cells were ENK-immunoreactive (IR). A dense network of ENK-IR nerves was localized among adrenaline cells. NT was localized only in the noradrenaline cells, 60%–70% of which were immunoreactive. NT- and ENK-IR were localized in separate noradrenaline cells. A dense network of NT-IR nerves was restricted among noradrenaline cells.

The present findings confirm that ENK- and NT-like peptides are localized in separate adrenal medullary cells and demonstrate that also the preganglionic nerves are divided in subpopulations according to their neuropeptide content. These nerves have a selective localization among adrenaline and noradrenaline cells and may have physiological significance in the control of secretion of catecholamines and neuropeptides from adrenal medulla.

Keywords

Public Health Peptide Noradrenaline Adrenaline Catecholamine 

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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • M. Pelto-Huikko
    • 1
  • T. Salminen
    • 1
  • A. Hervonen
    • 2
  1. 1.Department of Biomedical SciencesUniversity of TampereTampereFinland
  2. 2.Department of Public HealthUniversity of TampereTampereFinland

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