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Quantitative histochemical and stereological study of alkaline phosphatase in the rat thyroid gland

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Summary

The histochemical alkaline phosphatase reaction in thyroid vascular endothelium was estimated spectrophotometrically and stereologically. Thus two main characteristics of the reaction were obtained: 1. the average enzyme activity, reflecting the level of transport processes in the capillary-thyrocyte system; 2. the relative volume of functioning vessels. An index of thyroid vascularity is proposed that is equal to the product of these two characteristics. The changes of the primary characteristics as well as of the vascularity index, caused by experimental hypo- and hyperplasia of the gland, are discussed.

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Authors and Affiliations

  1. Department of Histology and Embryology and Department of Histochemistry, Central Laboratory for Medical Research, 1st Leningrad Medical Institute, SU-197089, Leningrad, USSR

    V. L. Bykov & V. A. Prianishnikov

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  1. V. L. Bykov
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  2. V. A. Prianishnikov
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Bykov, V.L., Prianishnikov, V.A. Quantitative histochemical and stereological study of alkaline phosphatase in the rat thyroid gland. Histochemistry 58, 129–134 (1978). https://doi.org/10.1007/BF00489958

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  • DOI: https://doi.org/10.1007/BF00489958

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