, Volume 79, Issue 2, pp 193–203 | Cite as

A cytochemical study of the effect of cholinergic and β-adrenergic stimulation on calcium fluxes of rat parotid gland

  • H. W. Sampson
  • D. J. Kiessel
  • L. MacKenzie-Graham
  • I. Piscopo


Parotid gland tissue from carbachol-treated and isoproterenol-treated rats was studied cytochemically by pyroantimonate precipitation and x-ray microanalysis in an effort to identify any intracellular calcium reservoirs that might be available for use in a stimulus-secretion coupling mechanism, and to determine any differences that might exist in terms of calcium utilization due to the cholinergic or β-adrenergic receptor mechanisms. Stimulation by either secretagogue results in a reduction of mitochondrial and plasma membrane calcium, but the reduction in mitochondrial calcium deposits of carbachol-treated animals is only one-half that of the β-adrenergic-treated animals. This could possibly suggest a greater dependency on mitochondrial calcium for β-adrenergic stimulated animals.


Parotid Gland Calcium Deposit Calcium Flux Gland Tissue Great Dependency 
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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • H. W. Sampson
    • 1
  • D. J. Kiessel
    • 1
  • L. MacKenzie-Graham
    • 1
  • I. Piscopo
    • 2
  1. 1.Department of Human AnatomyTexas A&M Medical SchoolCollege StationUSA
  2. 2.Philips Electronic Instruments Inc.MahwahUSA

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