Chemistry of Heterocyclic Compounds

, Volume 13, Issue 8, pp 875–877 | Cite as

Investigation of the direction of the Fischer cyclization of arylhydrazones that are derivatives of hexahydrobenz[e]indene cyclization of a piperidine-2,3-dione 3-hydrazone

  • V. I. Sladkov
  • O. S. Anisimova
  • N. N. Suvorov
Article
  • 28 Downloads

Abstract

The cyclization of the piperidine-2,3-dione 3-hydrazone obtained from the three-ring steroid BCD fragment proceeds with the primary formation of a p-substitution product. According to the PMR spectral data, the ratio of the para and ortho isomers is 3.3∶2.

Keywords

Indene Steroid Organic Chemistry Spectral Data Dione 

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Literature cited

  1. 1.
    V. I. Sladkov, V. F. Shner, O. S. Anisimova, L. M. Alekseeva, L. I. Lisitsa, A. I. Terekhina, and N. N. Suvorov, Zh. Org. Khim., 10, 1290 (1974).Google Scholar
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    B. Robinson, Chem. Rev., 69, 227 (1969).Google Scholar
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    Yu. P. Kitaev and B. I. Buzykin, Hydrazones [in Russian], Nauka, Moscow (1974), p. 235.Google Scholar

Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • V. I. Sladkov
    • 1
  • O. S. Anisimova
    • 1
  • N. N. Suvorov
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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