Investigation of the direction of the Fischer cyclization of arylhydrazones that are derivatives of hexahydrobenz[e]indene cyclization of a piperidine-2,3-dione 3-hydrazone
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The cyclization of the piperidine-2,3-dione 3-hydrazone obtained from the three-ring steroid BCD fragment proceeds with the primary formation of a p-substitution product. According to the PMR spectral data, the ratio of the para and ortho isomers is 3.3∶2.
KeywordsIndene Steroid Organic Chemistry Spectral Data Dione
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