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Investigations in the imidazole series

LXXV. Synthesis of 2-methylmercapto-3-acylmethyl(β-hydroxyalkyl)naphth[1,2-d]imidazoles and their conversion to naphth[1,2-d]imidazo[3,2-blimidazole and naphth[1,2-d]-imidazo[3,2-b]imidazoline derivatives

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Abstract

The reaction of 2-methylmercaptonaphth[1,2-d]imidazole with α-halo ketones, β-halo alcohols, and olefin oxides gave 2-methylmercapto-3-acylmethyl(β-hydroxyalkyl)naphth-[1,2-d]imidazoles. Their conversion to naphth[1,2-d]imidazo[3, 2-b]imidazole and naphth-[1,2-dlimidazo[3,2-b]imidazoline derivatives was studied.

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Literature cited

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Authors and Affiliations

  1. Zaporozhe Medical Institute, Moscow

    M. V. Povstyanoi & P. M. Kochergin

  2. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, Moscow

    M. V. Povstyanoi & P. M. Kochergin

Authors
  1. M. V. Povstyanoi
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  2. P. M. Kochergin
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Additional information

See [1] for communication LXXIV.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 816–819, June, 1972.

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Povstyanoi, M.V., Kochergin, P.M. Investigations in the imidazole series. Chem Heterocycl Compd 8, 738–741 (1972). https://doi.org/10.1007/BF00487472

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  • DOI: https://doi.org/10.1007/BF00487472

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