Chemistry of Heterocyclic Compounds

, Volume 26, Issue 5, pp 582–587 | Cite as

Basic hydrolysis of 3-acetoxy-7-bromo-5-(o-chlorophenyl)-1-ethoxycarbonylmethyl-1,2-dihydro-3H-1,4-benzadiazepin-2-one

  • A. A. Mazurov
  • A. A. Dvorkin
  • Yu. A. Simonov
  • S. A. Andronati
Article
  • 44 Downloads

Abstract

The selective basic hydrolysis of 3-acetoxy-7-bromo-5-(o-chlorophenyl)-1-ethoxycarbonylmethyl-1,2-dihydro-3H-1,4-benzdiazepin-2-one has been carried out, resulting in the sequential formation of 3-hydroxy-1-ethoxycarbonylmethyl-, 3-hydroxy-1-methoxycarbonylmethyl-, and 3-hydroxy-1-carboxymethyl derivatives. The structure of the 1-methoxycarbonylmethyl derivatives has been established by x-ray structural analysis.

Keywords

Hydrolysis Organic Chemistry Structural Analysis Sequential Formation Basic Hydrolysis 

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Copyright information

© Plenum Publishing Corporation 1990

Authors and Affiliations

  • A. A. Mazurov
    • 1
    • 2
  • A. A. Dvorkin
    • 1
    • 2
  • Yu. A. Simonov
    • 1
    • 2
  • S. A. Andronati
    • 1
    • 2
  1. 1.A. V. Bogatskii Physical Chemical InstituteAcademy of Sciences of the Ukrainian SSROdessa
  2. 2.Institute of Applied PhysicsAcademy of Sciences of the Moldavian SSRKishinev

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