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Synthesis of 4, 6-diphenacylpyrimidines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Reaction of 4,6-dimethylpyrimidine with the acyl chlorides of aromatic carboxylic acids gave N-acyl-4-phenacyl-6-acylmethylidynepyrimidines, which undergo alcoholysis to give the corresponding diketones — 4,6-diphenacylpyrimidines.

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  1. V. M. Cherkasov, L. P. Prikazchikova, B. M. Khutova, I. F. Vladimirtsev, and I. V. Boldyrev, Khim. Geterotsikl. Soedin., 1132 (1973).

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1146–1147, August, 1974.

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Prikazchikova, L.P., Khutova, B.M. & Cherkasov, V.M. Synthesis of 4, 6-diphenacylpyrimidines. Chem Heterocycl Compd 10, 998–999 (1974). https://doi.org/10.1007/BF00487130

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  • DOI: https://doi.org/10.1007/BF00487130

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