Abstract
The thermal condensation of halobenzylmalonic esters with phenol has given a series of 3-halobenzyl derivatives of 4-hydroxycoumarin. Alkaline hydrolysis, with simultaneous decarboxylation, gives the corresponding o-hydroxy-β-halophenylpropiophenones.
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References
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L. P. Zalukaev and M. P. Aleksyuk, Biologically Active Compounds [in Russian], Nauka, Moscow-Leningrad, p. 139, 1965.
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Zalukaev, L.P., Aleksyuk, M.P. Synthesis of 3-halobenzyl-4-hydroxycoumarins and their hydrolysis. Chem Heterocycl Compd 4, 696 (1968). https://doi.org/10.1007/BF00486931
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DOI: https://doi.org/10.1007/BF00486931