Autosomal determination of erythrocyte glucose 6-phosphate dehydrogenase in domestic chickens and ring-necked pheasants
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Erythrocyte glucose 6-phosphate dehydrogenase isozymes of domestic chickens, ring-necked pheasants, and their hybrids were studied, using the starch gel zone electrophoresis technique. In domestic chickens G6PD isozymes were represented by two fast-moving bands and an indistinct third band, whereas in ring-necked pheasants a slow-moving broad band which seemed to consist of two closely apposed G6PD isozymes was observed. The F1 hybrids showed three distinct bands combining the characteristic mobility pattern of the two parents, which seemed to indicate that both parental alleles are expressed in F1 hybrids. Since both male and female hybrids exhibited strikingly similar isozyme patterns representing both sire and dam, it was assumed that the genes controlling the production of G6PD in chicken and pheasant red blood cells are located on the autosomes.
KeywordsGlucose Starch Blood Cell Broad Band Mobility Pattern
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- Adam, A. (1961). Linkage between deficiency of glucose-6-phosphate dehydrogenase and colour blindness. Nature 189 686.Google Scholar
- Beutler, E., and Collins, Z. (1965). Hybridization of glucose-6-phosphate from rat and human erythrocytes. Science 150 1306.Google Scholar
- Childs, B., and Zinkham, W. H. (1959). The genetics of primaquine sensitivity of erythrocytes. In Ciba Foundation Symposium on Biochemistry of Human Genetics, J. and A. Churchill, London, pp. 76–89.Google Scholar
- Kirkman, H. N., and Hendrickson, E. M. (1963). Sex-linked electrophoretic differences in glucose-6-phosphate dehydrogenase activity. Am. J. Human Genet. 15 241.Google Scholar
- Mathai, C. K., Ohno, S., and Beutler, E. (1966). Sex-linkage of the glucose-6-phosphate dehydrogenase gene in equidae. Nature 210 115.Google Scholar
- Ohno, S. (1966). Cytologic and genetic evidence of somatic segregation in mammals, birds and fishes, in vitro. Publication of Tissue Culture Association, Vol. II, pp. 46–60.Google Scholar
- Ohno, S., Pool, J., and Gustavson, I. (1965). Sex-linkage of erythrocyte glucose-6-phosphate dehydrogenase in two species of wild hares. Science 150 1737.Google Scholar
- Shaw, C. R., and Barto, E. (1965). Autosomally determined polymorphism of glucose-6-phosphate dehydrogenase in Peromyscus. Science 148 1099.Google Scholar
- Young, W., Porter, J. E., and Childs, B. (1964). Glucose-6-phosphate dehydrogenase in drosophila. X-linked electrophoretic variants. Science 143 140.Google Scholar