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Biochemical Genetics

, Volume 13, Issue 5–6, pp 369–377 | Cite as

Esterase. XXI. Es-9, a possibly new polymorphic esterase in Mus musculus genetically linked to Es-2

  • J. Schollen
  • K. Bender
  • O. von Deimling
Article

Abstract

A so far undescribed gene controlling zone III esterases has been detected by means of disc gel electrophoresis of kidney homogenates from the two inbred mice strains NMRI and SK/Cam. The gene is tentatively designated Es-9, and the two codominant alleles are designated Es-9a and Es-9b. Es-9 esterases are present in many tissues, but, unlike the other zone III esterase (controlled by Es-5), are not found in the serum. Close linkage with the Es-2 gene leads us to map the Es-9 gene on chromosome 8.

Key words

esterase-9 Mus musculus kidney testosterone dependent linkage 

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References

  1. Chapman, V. M., Nichols, E. A., and Ruddle, F. H. (1974). Esterase-8 (Es-8): Characterization, polymorphism, and linkage of an erythrocyte esterase locus on chromosome 7 of Mus musculus. Biochem. Genet. 11347.Google Scholar
  2. Holt, S. J. (1958). Indigogenic staining methods for esterases. In Danielli, J. F. (ed.), General Cytochemical Methods, Vol. 1, Academic Press, New York, pp. 375–398.Google Scholar
  3. Huggins, C., and Lapides, J. (1947). Chromogenic substrates. IV. Acyl esters of p-nitrophenol as substrates for the colorometric determination of esterase. J. Biol. Chem. 170467.Google Scholar
  4. Maurer, H. R. (1971). Disc Electrophoresis and Related Techniques of Polyacrylamide Gel Electrophoresis, Walter de Gruyter, Berlin, New York.Google Scholar
  5. Petras, M. L. (1963). Genetic control of a serum esterase component in Mus musculus. Proc. Natl. Acad. Sci. 50112.Google Scholar
  6. Petras, M. L., and Biddle, F. G. (1967). Serum esterases in the house mouse, Mus musculus. Can. J. Genet. Cytol. 9704.Google Scholar
  7. Petras, M. L., and Sinclair, P. (1969). Another esterase variant in the kidney of the house mouse, Mus musculus. Can. J. Genet. Cytol. 1197.Google Scholar
  8. Popp, R. A. (1967). Linkage of Es-1 and Es-2 in the mouse. J. Hered. 58186.Google Scholar
  9. Popp, R. A., and Popp, D. M. (1962). Inheritance of serum esterases having different electrophoretic patterns among inbred strains of mice. J. Hered. 53111.Google Scholar
  10. Poulik, M. D. (1957). Starch gel electrophoresis in a discontinuous system of buffers. Nature 1801477.Google Scholar
  11. Roderick, T. H., Hutton, J. J., and Ruddle, F. H. (1970). Linkage of esterase-3 and rex on linkage group VII of the mouse. J. Hered. 61278.Google Scholar
  12. Ruddle, F. H. (1966). Kidney esterases of the mouse (Mus musculus): Electrophoretic analysis of inbred lines C57BL/6J, RF/J and SJL/J. J. Histochem. Cytochem. 1425.Google Scholar
  13. Ruddle, F. H., and Roderick, T. H. (1966). The genetic control of two types of esterase in inbred strains of the mouse. Genetics 54191.Google Scholar
  14. Ruddle, F. H., and Roderick, T. H. (1968). Allelically determined isozyme polymorphisms in laboratory populations of mice. Ann. N. Y. Acad. Sci., 151531.Google Scholar
  15. Ruddle, F. H., Shows, T. B., and Roderick, T. H. (1969). Esterase genetics in Mus musculus: Expression, linkage, and polymorphism of locus Es-2. Genetics 62393.Google Scholar
  16. Shaw, C. R. (1969). Isozymes: Classification, frequency, and significance. Int. Rev. Cytol. 25297.Google Scholar
  17. Wehler, E., Grossarth, C., and von Deimling, O. (1973). Esterase VI: Der Einfluss von Testosteron auf die unspezifische Carboxylesterase der Mäuseniere während der postnatalen Entwicklung. Histochemie 3347.Google Scholar
  18. Wienker, T., Forsgren, K., and von Deimling, O. (1973). Esterase XI: Histochemische, elektrophoretische und quantitative Befunde zum geschlechtsspezifischen Substratspaltmuster der unspezifischen Nierenesterase der Maus. Histochemie 37275.Google Scholar

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • J. Schollen
    • 1
  • K. Bender
    • 2
  • O. von Deimling
    • 1
  1. 1.Institute of Pathology (Ludwig-Aschoff-Haus)University of Freiburg i. Br.Germany
  2. 2.Institute of Human Genetics and AnthropologyUniversity of Freiburg i. Br.Germany

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