Biochemical Genetics

, Volume 13, Issue 5–6, pp 323–329 | Cite as

Polymorphism and linkage of glutathione reductase in Mus musculus

  • Elizabeth A. Nichols
  • Frank H. Ruddle


Using an electrophoretic variant for glutathione reductase, we have been able to map the structural gene for this enzyme to chromosome 8 in Mus musculus.

Key words

glutathione reductase electrophoretic variant mapped Mus musculus 


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  1. DeLorenzo, R. J., and Ruddle, F. H. (1970). Glutamate oxalate transaminase (GOT) genetics in Mus musculus: Linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci. Biochem. Genet. 4259.Google Scholar
  2. Jacob, H. S., and Jandl, J. H. (1966). Effects of sulfhydryl inhibition on red blood cells. III. Glutathione in the regulation of hexose monophosphate pathway. J. Biol. Chem. 2414243.Google Scholar
  3. Long, W. (1967). Glutathione reductase in red blood cells: Variant associated with gout. Science 255712.Google Scholar
  4. Nichols, E. A., and Ruddle, F. H. (1973). A review of enzyme polymorphism, linkage and electrophoretic conditions for mouse and somatic cell hybrids in starch gels. J. Histochem. Cytochem. 211066.Google Scholar

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • Elizabeth A. Nichols
    • 1
  • Frank H. Ruddle
    • 1
  1. 1.Department of BiologyYale UniversityNew Haven

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