Abstract
There are three electrophoretically separable sets of alcohol dehydrogenase isozymes in maize. Previous work has shown that two of these isozymes (Sets I and II) share a subunit in common, since mutations in one of the Adh genes, Adh 1, alter both isozymes. A mutation in the second Adh gene, Adh 2, has now been induced and recovered. This mutant allele also alters two of the three isozymes—Sets III and II. Adh 1 and Adh 2 appear to segregate independently. Gel filtration data show that all ADH isozymes are indistinguishable in size. These findings support the hypothesis that the two Adh genes specify promoters which homo- and heterodimerize, yielding three types of ADH isozymes.
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This research was supported by National Science Foundation Grant GB 25594. M.F. is a recipient of Public Health Service Genetics Training Grant GM 82-12.
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Freeling, M., Schwartz, D. Genetic relationships between the multiple alcohol dehydrogenases of maize. Biochem Genet 8, 27–36 (1973). https://doi.org/10.1007/BF00485554
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DOI: https://doi.org/10.1007/BF00485554