Abstract
Sorbitol dehydrogenase (SDH) found in liver, kidney, and gonads of the goldfish (Carassius auratus) appears to be specified by a single autosomally inherited gene locus and, when subjected to electrophoresis, SDH behaves as a tetramer in that a homozygote gives a single band, while a heterozygote shows five bands of SDH. In a population of the wild goldfish inhabiting Lake Erie, two alleles which specify electrophoretic variants SA and SB coexist in nearly equal frequency, and there appears to be a slight excess of heterozygotes. Sixty-seven of the 109 wild goldfish were SA/SB heterozygotes. In the domesticated goldfish, on the other hand, an allele for the SB variant appears to be a very rare allele. Only one of the 100 domesticated goldfish studied here and none of the 100 domesticated goldfish studied in Germany was an SA/SB heterozygote.
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Supported in part by a grant (CA 05138) and grant (FR 00433) from the National Cancer Institute, U.S. Public Health Service.
On leave from McMaster University, Hamilton, Ontario, Canada.
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Lin, CC., Schipmann, G., Kittrell, W.A. et al. The predominance of heterozygotes found in wild goldfish of lake Erie at the gene locus for sorbitol dehydrogenase. Biochem Genet 3, 603–607 (1969). https://doi.org/10.1007/BF00485482
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DOI: https://doi.org/10.1007/BF00485482