Abstract
Phenol oxidase activity of activated A1 and A2 (A3) electrophoretic components from 19 lozenge mutant and three lozenge double mutant strains was compared to that of wild type flies. Melanin production by the activated A components with tyrosine as substrate was compared to activity in the same acrylamide gels with dopa as substrate. Melanin production decreased, first in the A1 band and then in the A2 (A3) band, with increased morphological expression of the mutant genes. No melanin bands were obtained with either substrate in five of the more severely affected mutants. A possible correlation between phenol oxidase activity and quinone production necessary for normal development of eyes, female accessory sex organs, and claws is discussed.
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Peeples, E.E., Geisler, A., Whitcraft, C.J. et al. Activity of phenol oxidases at the puparium formation stage in development of nineteen lozenge mutants of Drosophila melanogaster . Biochem Genet 3, 563–569 (1969). https://doi.org/10.1007/BF00485477
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DOI: https://doi.org/10.1007/BF00485477