Biochemical Genetics

, Volume 1, Issue 3, pp 277–285 | Cite as

Nature of the heterozygote blood catalase in a hypocatalasemic mouse mutant

  • Robert N. Feinstein
  • Joann T. Braun
  • Judith B. Howard


The blood catalase of a hypocatalasemic mouse mutant has been compared with that of the wild-type (normal) animal and with that of the heterozygote. Comparison is on the basis of stability to heat and to urea. Electrophoretic evidence is of no value, because all forms tested show the same mobility. Because the heterozygote heat and urea inactivation curves differ from those of the two parental forms, and because the curves are smoothly S-shaped, with no shoulders or other irregularities, it is suggested that this heterozygote produces only a single molecular form of the enzyme.


Urea Catalase Mouse Mutant Parental Form Molecular Form 
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Copyright information

© Plenum Publishing Corporation 1968

Authors and Affiliations

  • Robert N. Feinstein
    • 1
  • Joann T. Braun
    • 1
  • Judith B. Howard
    • 1
  1. 1.Argonne National LaboratoryDivision of Biological and Medical ResearchArgonne

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