Abstract
A new esterase locus (Es-13) has been identified in Mus musculus. Strains AEJ/GnRk, LG/J, SJL/J, and SWR/J carry a recessive allele, Es-13 b, for a locus possibly involved in the posttranslational modification of a kidney esterase. All other strains observed carried the dominant Es-13 a allele. Es-13 was mapped on Chr 9 by recombinant inbred lines and by conventional backcrossing experiments. Backcross data produced the following gene order and map distances: Lap-1 (31.6±7.5 cM) Es-13 (2.6±2.6 cM) Mod-1.
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References
Nichols, E. A., Chapman, V. M., and Ruddle, F. H. (1973). Polymorphism and linkage for mannosephosphate isomerase in Mus musculus. Biochem. Genet. 847.
Peters, J., and Nash, H. R. (1977). Polymorphism of esterase 11 in Mus musculus, a further esterase locus on chromosome 8. Biochem. Genet. 15217.
Taylor, B.A. (1976). Genetic analysis of susceptibility to isoniazid-induced seizures in mice. Genetics 83373.
Taylor, B. A. (1977). Mouse News Lett. 5641.
Taylor, B. A., Bedigian, H. G., and Meier, H. (1977). Genetic studies of the Fv-1 locus of mice: Linkage with Gpd-1 in recombinant inbred lines. J. Virol. 23106.
Womack, J. E. (1975). Esterase-6 (Es-6) in laboratory mice: Hormone influenced expression and linkage relationships to oligosyndactylism (Os), esterase-1 (Es-1) and esterase-2 (Es-2) in Chromosome 8. Biochem. Genet. 13311.
Womack, J. E. (1976). Mouse News Lett. 5518.
Womack, J. E., and Sharp, M. (1976). Comparative autosomal linkage in mammals: Genetics of esterases in Mus musculus and Rattus norvegicus. Genetics 82665.
Womack, J. E., Lynes, M. A., and Taylor, B. A. (1975). Genetic variation of an intestinal leucine arylaminopeptidase (Lap-1) in the mouse and its location on chromosome 9. Biochem. Genet. 13511.
Womack, J. E., Davisson, M. T., Eicher, E. M., and Kendall, D. A. (1977). Mapping of nucleoside phosphorylase (Np-1) and esterase-10 (Es-10) on mouse chromosome 14. Biochem. Genet. 15347.
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This work was aided by a grant from the National Foundation-March of Dimes, by Grant GM-18684 from the National Institute of General Medical Sciences, by Grant 75-03397 from the National Science Foundation, and by Contract NO1-ES4-2159 with the National Institute of Environmental Health Sciences. The Jackson Laboratory is fully accredited by the American Association for Accreditation of Laboratory Animal Care.
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Womack, J.E., Taylor, B.A. & Barton, J.E. Esterase 13, a new mouse esterase locus with recessive expression and its genetic location on chromosome 9. Biochem Genet 16, 1107–1112 (1978). https://doi.org/10.1007/BF00484531
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DOI: https://doi.org/10.1007/BF00484531