Biochemical Genetics

, Volume 13, Issue 11–12, pp 789–803 | Cite as

Esterase polymorphism and sensitivity to dursban organophosphorus insecticide in Culex pipiens pipiens populations

  • Nicole Pasteur
  • Gilbert Sinègre


Esterase polymorphism and Dursban (O,O-dimethyl-2-pyridylphosphorothioate) sensitivity have been investigated in 12 natural populations and three laboratory strains of Culex pipiens pipiens. This mosquito has two esterase loci, Est-1 and Est-2, which were shown to code esterases of the B group (aliesterases) but not cholinesterases. No correlation between Est-1 polymorphism and Dursban sensitivity was found, but the increase of the Est-20.64 allele in the populations less sensitive to Dursban was highly significant (r=−0.9850 for 6 df).

Key words

Culex p. pipiens esterase polymorphism organophosphate sensitivity 


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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • Nicole Pasteur
    • 1
  • Gilbert Sinègre
    • 2
  1. 1.Laboratoire d'Ecologie MédicaleFaculté de MèdecineMontpellierFrance
  2. 2.Entente Interdépartementale pour la Démoustication du Littoral MéditerranéenMontpellierFrance

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