Biochemical Genetics

, Volume 16, Issue 3–4, pp 307–319 | Cite as

Inheritance and linkage analysis of five enzyme loci in interspecific hybrids of toadlets, genus Bombina

  • Jacek M. Szymura
  • Irena Farana


Progeny produced from Bombina bombina, B. variegata, and field-collected interspecific hybrids have been analyzed for the inheritance of five enzyme loci, which are fixed for alternate alleles in the parental species. Lactate dehydrogenase (Ldh-1), NAD-dependent malate dehydrogenase (Mdh-1), creatine kinase (Ck), adenylate kinase (Ak), and glucosephosphate isomerase (Gpi) are all inherited in a Mendelian manner as codominant alleles at nuclear loci. Both parental alleles are equally functional in artificial F1 hybrids (female B. bombina×male B. variegata) at each of the loci studied. No linkage between any pair of loci was observed. Discovery of this inherited biochemical variation combined with a technique for assaying individual genotypes without killing the animals makes feasible studies of hybrid population structure heretofore impossible.

Key words

Bombina hybrids allozymes genetics 


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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • Jacek M. Szymura
    • 1
  • Irena Farana
    • 1
  1. 1.Department of Comparative AnatomyJagellonian UniversityKrakówPoland

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