Biochemical Genetics

, Volume 15, Issue 9–10, pp 817–823 | Cite as

α1-Antitrypsin polymorphism in Malaysian Macaca irus

  • F. Kueppers
  • J. Ganesan


α1-Antitrypsin types were determined in 200 individual specimens of Malaysian Macaca irus. We found the pattern B in 76 samples, BC in 116, and C in 8. Assuming that these patterns are determined by codominant alleles at one locus, this distribution constitutes a significant (P<0.001) deviation from Hardy-Weinberg equilibrium, because of an excess of BC and low prevalence of C. We found no clear evidence for the presence of α1-antitrypsin deficiency comparable to the situation in man.

Key words

α1-antitrypsin types serum trypsin inhibiting activity Malaysian Macaca irus 


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Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • F. Kueppers
    • 1
  • J. Ganesan
    • 2
  1. 1.Mayo Clinic and Mayo FoundationRochester
  2. 2.Institute for Medical ResearchJalan Pahang, Kuala LumpurMalaysia

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