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Linkage of the structural gene for uroporphyrinogen I synthase to markers on mouse chromosome 9 in a cross between feral and inbred mice

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Abstract

The Ups locus has been mapped to mouse chromosome 9 in a three-point cross. The observed gene order is centromere-Ups-15-Mpi-1-22-Mod-1. Ups is unlinked to Lv, which encodes the previous enzyme in the heme biosynthesis pathway. Feral mice collected at Skive, Denmark, have been characterized at several biochemical loci; multiple differences from inbred strains make this a useful stock for linkage analysis.

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Supported by USPHS Grants GM 24872 and GM 19521.

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Antonucci, T.K., Chapman, V.C. & Meisler, M.H. Linkage of the structural gene for uroporphyrinogen I synthase to markers on mouse chromosome 9 in a cross between feral and inbred mice. Biochem Genet 20, 703–710 (1982). https://doi.org/10.1007/BF00483967

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  • DOI: https://doi.org/10.1007/BF00483967

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