Skip to main content
SpringerLink
Log in

Hematological and physiological responses to sublethal concentrations of cadmium in a freshwater teleost, Tilapia zillii

  • Published:
Water, Air, and Soil Pollution Aims and scope Submit manuscript

Abstract

Blood from Tilapia zillii exposed to three sublethal concentrations of Cd (10.62, 17.70 and 24.78 mg L−1) for 24, 48, 72 and 96 hr was analyzed to identify and evaluate changes in erythrocyte count (RBC), hematocrit (Ht), hemoglobin (Hb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), erythrocyte sedimentation rate (ESR), leucocyte count (WBC), differential leucocyte counts, total protein, glucose and lactic acid. Hematological and physiological changes attributable to Cd poisoning were observed. Fish showed obvious signs of stress at 17.70 and 24.78 mg L−1 Cd. Clear time related effects of Cd on the biochemical factors were recorded. The severe stress conditions caused by Cd may be responsible for the hematological and physiological changes in blood.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Agrawal, S. J., Srivastava, A. K., and Chaudhry, H. S.: 1979, Acta Pharmacol. Toxicol. 45, 215.

    Google Scholar 

  • American Public Health Association: 1965, Standard Methods for the Examination of Water and Wastewater, 12th ed., APHA, New York, p. 769.

    Google Scholar 

  • Barker, S. B.: 1963, in S. P. Colowick and N. O. Kaplan (eds.), Methods in Enzymology, Academic press, New York 3, 241.

    Google Scholar 

  • Bremner, I. and Marshall, R. B.: 1974, Br. J. Nutr. 32, 293.

    Google Scholar 

  • Chapatwala, K. D., Rajanna, B., and Desaiah, D.: 1980, Drug Chem. Toxicol. 8, 407.

    Google Scholar 

  • Chaudhry, H. S.: 1984, Toxicol. Lett. 20, 115.

    Google Scholar 

  • Dalwani, R., Dava, J. M., and Datta, K.: 1985, Biochem. Int. 10, 33.

    Google Scholar 

  • Dheer, J. M. S.: 1988, J. Fish. Biol. 32, 197.

    Google Scholar 

  • Donaldson, E. M.: 1981, in A. D. Pickering (ed.), Stress and fish, Academic Press, London, p. 11.

    Google Scholar 

  • Donaldson, E. M. and Dye, H. M.: 1975, J. Fish. Res. Bd Can. 32, 533.

    Google Scholar 

  • Ellis, A. E.: 1981, in A. D. Pickering (ed.), Stress and Fish, Academic Press, London, p. 147.

    Google Scholar 

  • El Nabawi, A., Heinzow, B., and Kruse, H.: 1987, Bull. Environ. Contain. Toxicol. 39, 889, Res. 4, 71.

    Google Scholar 

  • Flos, R., Tort, L., and Balasch, J.: 1987, Mar. Environ. Res. 21, 289.

    Google Scholar 

  • Forstner, U. and Wittmann, G. T. W.: 1981, Metal Pollution in the Aquatic Environment, Berlin: Springer.

    Google Scholar 

  • Friberg, L., Piscator, M., and Nordberg, G. F.: 1971, Cadmium in the Environment. CRC Press, Cleveland, Ohio.

    Google Scholar 

  • Frovola, L. K.: 1960, Dokl. Akad. Nauk SSSR 131, 983.

    Google Scholar 

  • Fulkerson, W. and Goeller, H. E.: 1972, Cadmium: The Dissipated Element. Oake Ridge National Laboratory. ORNL NSF-EP-21.

  • Ghazaly, K. S.: 1991, Proc. Zool. Soc. A.R.E. (in press).

  • Goldberg, E. D.: 1984, Mar. Poll. Bull. 15, 163.

    Google Scholar 

  • Goodman, L. S. and Gilman, A.: 1960, The Pharmacological Basis of Therapeutics, 2nd ed., Macmillan, New York, p. 994.

    Google Scholar 

  • Griboff, S., Harman, A., and Brickman, S.: 1968, Medical Times 96, 1008.

    Google Scholar 

  • Heath, A. G.: 1984, J. Fish. Biol. 24, 299.

    Google Scholar 

  • Hesser, E. F.: 1960, Progr. Fish Cult. 22, 164.

    Google Scholar 

  • Hllge, V., Delventhal, H., and Klinger, H.: 1981, in K. Tiews (ed.), Aquaculture in Heated Effluents and Recirculation Systems, Berlin: Heenemann Verlagsgesellschaft 2, 185.

    Google Scholar 

  • Hilmy, A. M., Shabana, M. B., and Saied, M. M.: 1980, Water, Air, and Soil Pollut. 14, 409.

    Google Scholar 

  • Hughes, G. M.: 1981, in A. D. Pickering (ed.), Stress and Fish, Academic Press, London, p. 121.

    Google Scholar 

  • Koyama, J. and Ozaki, H.: 1984, Bull. Jap. Soc. Scient. Fish 50, 199.

    Google Scholar 

  • Larsson, A.: 1973, Gen. Comp. Endocrinol. 20, 155.

    Google Scholar 

  • Lewis, S. D. and Lewis, V. M.: 1971, Trans. Am. Fish. Soc. 100, 639.

    Google Scholar 

  • Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R.: 1951, J. Biol. Chem. 193, 265.

    Google Scholar 

  • Matthiessen, P.: 1981, J. Fish. Biol. 18, 461.

    Google Scholar 

  • McKee, J. E. and Wolf, H. W.: 1963, Water Quality Criteria, 2nd ed., The Resources Agency of California, State Water Quality Control Board Publ. No. 3-A., p. 548.

  • McKim, J. M., Olson, G. F., Holcombe, G. W., and Hunt, E. P.: 1976, J. Fish. Res. Bd Can. 33, 2726.

    Google Scholar 

  • McLeay, D. J.: 1973, J. Fish. Res. Bd Can. 30, 395.

    Google Scholar 

  • McLeay, D. J.: 1975, J. Fish. Res. Bd Can. 32, 2357.

    Google Scholar 

  • McLeay, D. J. and Gordon, M. R.: 1977, J. Fish. Res. Bd Can. 34, 2164.

    Google Scholar 

  • Medi-Chem. K.: 1977, Med. Chem. Corp., Santa Monica, California, U.S.A.

  • Mishra, S. and Srivastava, A. K.: 1979, Bull. Environ. Contam. Toxicol. 22, 695.

    Google Scholar 

  • Mishra, S. and Srivastava, A. K.: 1980, Ecotoxicol. Environ. Saf. 4, 191.

    Google Scholar 

  • Pickering, Q. H. and Gast, M. H.: 1972, J. Fish. Res. Bd Can. 29, 1099.

    Google Scholar 

  • Pickering, Q. H. and Henderson, C.: 1965, Proc. 19th Ind. Waste Conf. Purdue Univ. 49, 578.

    Google Scholar 

  • Schroeder, H. A.: 1960, in M. J. Seven (ed.), Metal-Binding in Medicine, Lippincott, Philadelphia, p. 59.

    Google Scholar 

  • Skidmore, J. F.: 1970, J. Exp. Biol. 52, 481.

    Google Scholar 

  • Soivio, A. and Oikari, A.: 1976, J. Fish. Biol. 8, 397.

    Google Scholar 

  • Srivastava, A. K. and Agrawal, U.: 1977, Arch. Anat. Micros. Morphol. Exp. 66, 97.

    Google Scholar 

  • Srivastava, A. K. and Agrawal, S. J.: 1979, Acta Pharmacol. Toxicol. 44, 197.

    Google Scholar 

  • Srivastava, A. K., Agrawal, S. J., and Chaudhry, H. S.: 1979, Ecotoxicol. Environ. Saf. 3, 321.

    Google Scholar 

  • Steele, C. W.: 1983, Mar. Pollut. Bull. 14, 425.

    Google Scholar 

  • Tort, L. and Torres, P.: 1988, J. Fish Biol. 32, 277.

    Google Scholar 

  • Tort, L., Torres, P., and Hidalgo, J.: 1984, Mar. Pollut. Bull. 15, 448.

    Google Scholar 

  • Uthe, J. F. and Chou, C. L.: 1987, Can. J. Fish. Aquat. Sci. 44, 91.

    Google Scholar 

  • Versteeg, D. J. and Giesy, J. P.: 1986, Ecotoxicol. Environ. Safety 11, 31.

    Google Scholar 

  • Waiwood, K. G.: 1980, Trans. Am. Fish. Soc. 109, 461.

    Google Scholar 

  • Webb, M. and Verschoyle, R. D.: 1976, Biochem. Pharmacol. 25, 673.

    Google Scholar 

  • Wintrobe, M. M.: 1965, Clinical Haematology, Lea-Febiger, Philadelphia.

    Google Scholar 

Download references

Author information

Author notes

  1. K. S. Ghazaly

    Present address: Biology Dept., Centre of Sci. & Math., P.O. Box 1070, Taif, Saudi Arabia

Authors and Affiliations

  1. Department of Natural History, Faculty of Education, University of Alexandria, Alexandria, Egypt

    K. S. Ghazaly

Authors
  1. K. S. Ghazaly
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ghazaly, K.S. Hematological and physiological responses to sublethal concentrations of cadmium in a freshwater teleost, Tilapia zillii. Water Air Soil Pollut 64, 551–559 (1992). https://doi.org/10.1007/BF00483365

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00483365

Keywords

Search

Navigation