Chemistry of Heterocyclic Compounds

, Volume 13, Issue 4, pp 408–409 | Cite as

Research on 2,3-polymethylenequinolines

XXI Ionization constants of 4-chloro-6-R-2,3-polymethylenequinolines
  • M. E. Konshin
  • É. S. Abramochkin
  • D. I. Uvarov
Article
  • 22 Downloads

Abstract

The ionization constants of 4-chloro-6-R-2,3-polymethylenequinolines in 98% methanol were found and it was established that they correlate with the σepi substituent constants for quinoline. It is shown that the pK a values of 2,3-tetra- and 2,3-pentamethylenequinolines are close to one another, whereas the pK a values of 2,3-trimethylenequinolines are one order of magnitude lower; this is a result of the angular strain in the ring system of the latter.

Keywords

Methanol Organic Chemistry Quinoline Ring System Ionization Constant 

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Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • M. E. Konshin
    • 1
  • É. S. Abramochkin
    • 1
  • D. I. Uvarov
    • 1
  1. 1.Perm Pharmaceutical InstitutePerm

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