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The synthesis of xanthine-8-acetic acid and some of its derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Condensation of 5,6-diaminouracil with ethyl cyanoacetate yields xanthine-8-acetonitrile which is hydrolyzed by alkalis to xanthine-8-acetic acid. Also synthesized were its ethyl ester, acid chloride, and bis(2′-hydroxyethyl)amide.

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References

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Authors and Affiliations

  1. Lensovet Leningrad Technological Institute, USSR

    E. P. Studentsov & V. G. Nemets

Authors
  1. E. P. Studentsov
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  2. V. G. Nemets
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Studentsov, E.P., Nemets, V.G. The synthesis of xanthine-8-acetic acid and some of its derivatives. Chem Heterocycl Compd 4, 676–677 (1971). https://doi.org/10.1007/BF00481056

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  • DOI: https://doi.org/10.1007/BF00481056

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