Abstract
The reaction of the sodium salt of 2-mercapto-6-methyluracil with α, ω-dibromoalkanes Br(CH2)πBr (n=1,4,5,6) has given the corresponding α, ω-bis(4-hydroxy-6-methyl-2-pyrimidinylthio) alkanes. The reaction of the same salt with 1,2-dibromoethane gave 7-methyl-5-oxo-2,3,4,5-tetrahydrothiazolo[3,2-a]pyrimidine and 5-methyl-7-oxo-2,3,4,7-tetrahydrothiazolo[3,2-a]pyrimidine, and its reaction with 1,3-dibromopropane led to 8-methyl-6-oxo-3,4,5,6-tetrahydro-2H-pyrimidino[2,1-b]-1,3-thiazine.
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Pashkurov, N.G., Reznik, V.S. Derivatives of 2-mercapto-6-methyluracil. Chem Heterocycl Compd 4, 664–666 (1971). https://doi.org/10.1007/BF00481052
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DOI: https://doi.org/10.1007/BF00481052