Chemistry of Heterocyclic Compounds

, Volume 4, Issue 5, pp 561–563 | Cite as

Polyfluorinated heterocyclic compounds

II. Preparation of heterocyclic compounds based on α-benzamido-β-(pentafluorophenyl) acrylic acid
  • T. D. Petrova
  • V. P. Mamaev
  • G. G. Yakobson
  • N. N. VorozhsovJr.


A study has been made of the possibility of intramolecular cyclization of α-benzamido-β-(pentafluorophenyl)acrylic acid (IIa) with the object of synthesizing heterocyclic compounds. When the acid IIa was heated with potassium fluoride in dimethylformamide, 3-benzamido-6,7,8,9-tetrafluorocoumarin (III) was formed. Under the same conditions the methyl ester of (IIa) gave 2-phenyl-4-carbomethoxy-6,7,8,9-tetrafluorobenz[f]oxazepine-1,3 (Va). Some reactions of the latter have been studied.


Methyl Ester Potassium Organic Chemistry Fluoride 
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Copyright information

© Consultants Bureau 1971

Authors and Affiliations

  • T. D. Petrova
    • 1
  • V. P. Mamaev
    • 1
  • G. G. Yakobson
    • 1
  • N. N. VorozhsovJr.
    • 1
  1. 1.Novosibirsk Institute of Organic Chemistry, Siberian DivisionAcademy of SciencesUSSR

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