Chemistry of Heterocyclic Compounds

, Volume 2, Issue 2, pp 199–201 | Cite as

Researches on allo- and isoalloxazine

XIV. Synthesis of 6-chloro-7-sulfoamidoalloxazine and its N-oxide
  • V. M. Berezovskii
  • G. D. Glebova
  • N. V. Fedorova
  • Zh. I. Aksel'rod


For a study of the diuretic properties of alloxazine, 6-chloro-7-sulfamidoalloxazine (II) has been synthesized for the first time, by condensing 4-chloro-5-sulfamido-o-phenylenediamine with violuric acid, and 6-chloro-7-sulfamidoalloxazine N-oxide (IV) is prepared by oxidizing II with permonosulfuric acid at the instant of formation. The structure of II is shown by splitting it with sulfuric acid to 2-amino-6-chloroquinoxaline.


Organic Chemistry Sulfuric Acid Allo Diuretic Property Violuric Acid 
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Copyright information

© The Faraday Press, Inc. 1967

Authors and Affiliations

  • V. M. Berezovskii
    • 1
  • G. D. Glebova
    • 1
  • N. V. Fedorova
    • 1
  • Zh. I. Aksel'rod
    • 1
  1. 1.All-Union Vitamin Scientific Research InstituteMoscow

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