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Chemistry of Heterocyclic Compounds

, Volume 2, Issue 2, pp 199–201 | Cite as

Researches on allo- and isoalloxazine

XIV. Synthesis of 6-chloro-7-sulfoamidoalloxazine and its N-oxide
  • V. M. Berezovskii
  • G. D. Glebova
  • N. V. Fedorova
  • Zh. I. Aksel'rod
Article
  • 33 Downloads

Abstract

For a study of the diuretic properties of alloxazine, 6-chloro-7-sulfamidoalloxazine (II) has been synthesized for the first time, by condensing 4-chloro-5-sulfamido-o-phenylenediamine with violuric acid, and 6-chloro-7-sulfamidoalloxazine N-oxide (IV) is prepared by oxidizing II with permonosulfuric acid at the instant of formation. The structure of II is shown by splitting it with sulfuric acid to 2-amino-6-chloroquinoxaline.

Keywords

Organic Chemistry Sulfuric Acid Allo Diuretic Property Violuric Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    H. G. Petering and G. J. Van Giessen, J. Org. Chem., 26, 2818, 1961.Google Scholar
  2. 2.
    M. N. Shchukina, Med. prom., no. 4, 7, 1963.Google Scholar
  3. 3.
    V. M. Berezovskii and G. D. Glebova, DAN, 146, 355, 1962.Google Scholar
  4. 4.
    S. M. Gadekar and J. L. Frederick, J. Org. Chem., 27, 1383, 1962.Google Scholar
  5. 5.
    H. G. Petering, U.S. Patent no. 2973 359 (1961); RZhKh, 1962, Z1313.Google Scholar
  6. 6.
    E. Ochiai, J. Org. Chem., 18, 534, 1953.Google Scholar
  7. 7.
    A. S. Elina and O. Yu. Magidson, ZhOKh, 25, 161, 1955.Google Scholar
  8. 8.
    V. M. Berezovskii, Chemistry of Vitamins [in Russian], Pishchepromizdat, Moscow, 1959.Google Scholar
  9. 9.
    K. Pfister and J. Weijlard, U.S. Patent no. 2 650 221, 1953; C. A., 48, 11502, 1954.Google Scholar

Copyright information

© The Faraday Press, Inc. 1967

Authors and Affiliations

  • V. M. Berezovskii
    • 1
  • G. D. Glebova
    • 1
  • N. V. Fedorova
    • 1
  • Zh. I. Aksel'rod
    • 1
  1. 1.All-Union Vitamin Scientific Research InstituteMoscow

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