Chemistry of Heterocyclic Compounds

, Volume 2, Issue 2, pp 152–155 | Cite as

Formation of salts from acetyl- and formylpyrroles, and pyrrole ring reactivity

  • Yu. E. Sklyar
  • R. P. Evstigneeva
  • N. A. Preobrazhenskii
Article
  • 37 Downloads

Abstract

With 2-acetyl- and 2-formylpyrrole, salt formation is via proton addition to the carbonyl oxygen. In salt formation with pyrrole derivatives having an acetyl or formyl group at position 2, position 5 is deactivated for electrophilic substitution. With salts of 3-acetyl- and 3-formylpyrroles, position 2 is also deactivated, while position 5 is activated.

Keywords

Oxygen Organic Chemistry Carbonyl Acetyl Pyrrole 

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Copyright information

© The Faraday Press, Inc. 1967

Authors and Affiliations

  • Yu. E. Sklyar
    • 1
  • R. P. Evstigneeva
    • 1
  • N. A. Preobrazhenskii
    • 1
  1. 1.Lomonosov Institute of Fine Chemicals TechnologyMoscow

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