Chemistry of Heterocyclic Compounds

, Volume 2, Issue 2, pp 152–155 | Cite as

Formation of salts from acetyl- and formylpyrroles, and pyrrole ring reactivity

  • Yu. E. Sklyar
  • R. P. Evstigneeva
  • N. A. Preobrazhenskii


With 2-acetyl- and 2-formylpyrrole, salt formation is via proton addition to the carbonyl oxygen. In salt formation with pyrrole derivatives having an acetyl or formyl group at position 2, position 5 is deactivated for electrophilic substitution. With salts of 3-acetyl- and 3-formylpyrroles, position 2 is also deactivated, while position 5 is activated.


Oxygen Organic Chemistry Carbonyl Acetyl Pyrrole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© The Faraday Press, Inc. 1967

Authors and Affiliations

  • Yu. E. Sklyar
    • 1
  • R. P. Evstigneeva
    • 1
  • N. A. Preobrazhenskii
    • 1
  1. 1.Lomonosov Institute of Fine Chemicals TechnologyMoscow

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