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Pyrimidines

XL. Reaction of bisureas with isomeric hydroxyaminopyrazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

It is shown that the reaction of benzalbisurea with 3-amino-5-hydroxy-1-R-pyrazoles gives 1-R-dipyrazolo[3,4-b:4′,3′-e]pyridine (R=CH3) or a spiro(pyrazole-4,5′-pyrimidine) derivative (R=C6H5). Similar reactions of benzalbisurea with 3-hydroxy-5-amino-1-methylpyrazole give 2-methyldipyrazole[3,4-b:4′,3′-e]pyridine or substituted tetrahydropyrazolo[3,4-d] pyrimidine. Only the corresponding dipyrazolo[3,4-b:4′,3′-e]pyridines are formed in the reaction of 1-methylhydroxyaminopyrazoles with methylenebisurea.

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Authors and Affiliations

  1. Novosibirsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, USSR

    M. A. Mikhaleva, L. N. Il'chenko & V. P. Mamaev

Authors
  1. M. A. Mikhaleva
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  2. L. N. Il'chenko
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  3. V. P. Mamaev
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Additional information

See [1] for communication XXXIX.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 823–827, June, 1974.

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Mikhaleva, M.A., Il'chenko, L.N. & Mamaev, V.P. Pyrimidines. Chem Heterocycl Compd 10, 715–719 (1974). https://doi.org/10.1007/BF00480934

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  • DOI: https://doi.org/10.1007/BF00480934

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