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4-Trifluoromethylpyrimidines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

It is shown that Β-alkoxyvinyl trifluoromethyl ketones are convenient reagents for the synthesis of 4-trifluoromethylpyrimidines that contain a hydrogen atom or hydroxy, mercapto, and amino groups in the 2 position. The NMR, IR, and UV spectra of the synthesized compounds were studied. The absorption bands in the IR spectra of some of the 4-trifluoromethylpyrimidines were assigned empirically.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry, Academy of Sciences of the Ukrainian SSR, 252660, Kiev

    I. I. Gerus, S. I. Vdovenko, M. G. Gorbunova & V. P. Kukhar'

Authors
  1. I. I. Gerus
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  2. S. I. Vdovenko
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  3. M. G. Gorbunova
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  4. V. P. Kukhar'
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 502–511, April, 1991.

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Gerus, I.I., Vdovenko, S.I., Gorbunova, M.G. et al. 4-Trifluoromethylpyrimidines. Chem Heterocycl Compd 27, 398–406 (1991). https://doi.org/10.1007/BF00480838

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  • DOI: https://doi.org/10.1007/BF00480838

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