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Chemistry of Heterocyclic Compounds

, Volume 6, Issue 9, pp 1131–1135 | Cite as

Indole derivatives

LIV. Synthesis of 3, 5-diacetylindole
  • V. G. Avramenko
  • G. S. Mosina
  • N. N. Suvorov
Article
  • 43 Downloads

Abstract

3, 5-Diacetylinodole has been synthesized by three routes: acetylation of 5-acetylindole with acetic anhydride; reaction of 5-acetylindole with dimethylacetamide in the presence of phosphoryl chloride; and cyclization of biacetyl p-acetylphenylhydrazone with polyphosphoric acid. 5-Acetylindole was obtained by cyclizing ethyl pyruvate p-acetylphenylhydrazone.

Keywords

Acetic Chloride Ethyl Organic Chemistry Pyruvate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Consultants Bureau 1973

Authors and Affiliations

  • V. G. Avramenko
    • 1
  • G. S. Mosina
    • 1
  • N. N. Suvorov
    • 1
  1. 1.Mendeleev Moscow Chemical Technology InstituteUSSR

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