Chemistry of Heterocyclic Compounds

, Volume 6, Issue 9, pp 1131–1135 | Cite as

Indole derivatives

LIV. Synthesis of 3, 5-diacetylindole
  • V. G. Avramenko
  • G. S. Mosina
  • N. N. Suvorov


3, 5-Diacetylinodole has been synthesized by three routes: acetylation of 5-acetylindole with acetic anhydride; reaction of 5-acetylindole with dimethylacetamide in the presence of phosphoryl chloride; and cyclization of biacetyl p-acetylphenylhydrazone with polyphosphoric acid. 5-Acetylindole was obtained by cyclizing ethyl pyruvate p-acetylphenylhydrazone.


Acetic Chloride Ethyl Organic Chemistry Pyruvate 
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Copyright information

© Consultants Bureau 1973

Authors and Affiliations

  • V. G. Avramenko
    • 1
  • G. S. Mosina
    • 1
  • N. N. Suvorov
    • 1
  1. 1.Mendeleev Moscow Chemical Technology InstituteUSSR

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