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Chemistry of Heterocyclic Compounds

, Volume 11, Issue 5, pp 567–570 | Cite as

Research on arylhydrazones of substituted glyoxylic acids

XXI. Nitrogen-containing heterocycles with arylhydrazone groups
  • R. G. Dubenko
  • V. D. Konysheva
  • P. S. Pel'kis
Article
  • 40 Downloads

Abstract

3-Aryl-4-(arylhydrazonochloroformyl)-2-[(carbethoxy or carbarnoyl)cyanomethylene]-4-thiazolines were obtained by condensation of arylhydrazones of chloromethylglyoxylic chloride with arylamides of cyanomonothiomalonic acid ethyl ester or amide. The chlorine atom in these compounds is readily exchanged by a hydrazino group to give 3-aryl-4-(arylhydrazonohydrazinoformyl)-2-[(carbethoxy or carbamoyl)cyanomethylene]-4-thiazolines. 2-(Arylhydrazonocarbethoxyformyl)-4-(arylhydrazonochloroformyl)thiazoles were obtained by reaction of arylhydrazones of chloromethylglyoxylic chlorides with arylhydrazones of monothiomesoxalic acid ethyl ester amide. Arylhydrazones of ethyl 1H-tetrazolyl-5-glyoxylate were synthesized by condensation of arylhydrazones of ethyl cyanoglyoxylate with ammonium azide in dimethylformamide.

Keywords

Ammonium Ester Ethyl Amide Chlorine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

  1. 1.
    R. G. Dubenko and E. F. Gorbenko, Khim. Geterotsikl. Soedin., 346 (1975).Google Scholar
  2. 2.
    A. A. Grabenko, L. N. Kulaeva, and P. S. Pel'kis, Zh. Obshch. Khim., 32, 2248 (1962).Google Scholar
  3. 3.
    A. A. Grabenko, L. N. Kulaeva, and P. S. Pel'kis, Khim. Geterotsikl. Soedin., 698 (1965).Google Scholar
  4. 4.
    R. G. Dubenko and P. S. Pel'kis, Zh. Organ. Khim., 1, 1255 (1965).Google Scholar
  5. 5.
    R. G. Dubenko, V. D. Konysheva, V. M. Neplyuev, and P. S. Pel'kis, Zh. Organ. Khim., 7, 1932 (1971).Google Scholar
  6. 6.
    R. G. Dubenko and P. S. Pel'kis, Zh. Organ., Khim., 1, 1762 (1965).Google Scholar
  7. 7.
    R. G. Dubenko, Zh. Organ. Khim., 2, 485 (1966).Google Scholar
  8. 8.
    R. G. Dubenko, E. F. Gorbenko, V. D. Panchenko, and P. S. Pel'kis, Khim. Geterotsikl. Soedin., 740 (1969).Google Scholar
  9. 9.
    R. G. Dubenko and E. F. Gorbenko, Zh. Organ. Khim., 1, 2171 (1965).Google Scholar
  10. 10.
    R. G. Dubenko, E. F. Gorbenko, and P. S. Pel'kis, USSR Author's Certificate No. 169,533 (1964); Byul. Izobr., No. 7 (1965).Google Scholar
  11. 11.
    R. G. Dubenko and E. F. Gorbenko, Khim. Geterotsikl. Soedin., 923 (1967).Google Scholar
  12. 12.
    M. N. Shchukina, Materials on the Exchange of Experience and Scientific Achievements in the Pharmaceutical-Chemical Industry, No. 1, Moscow (1958), p. 123.Google Scholar
  13. 13.
    I. Ya. Postovskii and M. I. Ermakova, Zh. Obshch. Khim., 29, 1333 (1959).Google Scholar
  14. 14.
    G. A. Belonozhko, V. I. Vitte, R. G. Dubenko, L. K. Klimova, and P. S. Pel'kis, in: Physiologically Active Substances [in Russian], Vol. 1, Kiev (1966), p. 10.Google Scholar

Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • R. G. Dubenko
    • 1
  • V. D. Konysheva
    • 1
  • P. S. Pel'kis
    • 1
  1. 1.Institute of Organic ChemistryAcademy of Sciences of the Ukrainian SSRKiev

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