Abstract
The reaction of 5-amino-6-mercaptopyrimidines with 1,3-dimethyl-5-nitro-6-chlorouiracil in the presence of bases results in derivatives of 6,7,8,9-tetrahydrodipyrimido[4,5-b][4′,5′-e][1,4]-thiazine. If the 5-amino-6-mercaptopyrimdine contains a free or alkyl-substituted amino group at the 4-position, the tetrahydrodipyramidothiazines formed exist in a free radical form. The structure of the compounds formed has been established by spectral methods.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 258–264, February, 1989.
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Nemeryuk, M.P., Traven', N.I., Arutyunyan, T.G. et al. 6,7,8,9-Tetrahydrodipyrimido[4,5-b][4′,5′-e][1,4]thiazine derivatives. Synthesis and structure. Chem Heterocycl Compd 25, 214–220 (1989). https://doi.org/10.1007/BF00479922
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DOI: https://doi.org/10.1007/BF00479922