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Synthesis and properties of N(7)-Β-D-glucofuranouronosides of theophyllin and 3-isobutyl-1-methylxanthine

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Condensation of the trimethylsilyl derivatives of theophyllin and 3-isobutyl-1-methylxanthine with Β-D-glucofuranourono-6,3-lactone in the presence of trimethylsilyl trifluoromethanesulfonate has given N(7)-Β-D-glucofuranouronosides. Their hydrolytic stability has been examined at pH 1.4 and 7.4.

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Literature Cited

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Authors and Affiliations

  1. Institute of Organic Synthesis, Academy of Sciences of the Latvian SSR, 226006, Riga

    Yu. A. Maurin'sh, R. A. Paégle, V. D. Grigor'eva, O. V. Sakhartova, I. A. Mikhailopulo & M. Yu. Lidak

  2. Institute of Bioorganic Chemistry, Academy of Sciences of the Belorussin SSR, 220600, Minsk

    Yu. A. Maurin'sh, R. A. Paégle, V. D. Grigor'eva, O. V. Sakhartova, I. A. Mikhailopulo & M. Yu. Lidak

Authors
  1. Yu. A. Maurin'sh
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  2. R. A. Paégle
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  3. V. D. Grigor'eva
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  4. O. V. Sakhartova
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  5. I. A. Mikhailopulo
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  6. M. Yu. Lidak
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 241–245, February, 1989.

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Maurin'sh, Y.A., Paégle, R.A., Grigor'eva, V.D. et al. Synthesis and properties of N(7)-Β-D-glucofuranouronosides of theophyllin and 3-isobutyl-1-methylxanthine. Chem Heterocycl Compd 25, 198–202 (1989). https://doi.org/10.1007/BF00479918

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  • DOI: https://doi.org/10.1007/BF00479918

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