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Naphthyridines. 14. 2-Methylquinoline-3-carboxanilides and the synthesis therefrom of 2-substituted 1-oxo-3-phenyl-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 2-aminobenzaldehyde with acetoacetanilides has given 2-methylquinoline-3-carboxanilides. Condensation of these with benzaldehydes gives 2-styryl-quinoline-3-carboxanilides, which on heating in polyphosphoric acid cyclize to 2-substituted 1-oxo-3-phenyl-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridines.

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For Part 13, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 238–240, February, 1989.

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Ukhov, S.V., Konshin, M.E. Naphthyridines. 14. 2-Methylquinoline-3-carboxanilides and the synthesis therefrom of 2-substituted 1-oxo-3-phenyl-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridines. Chem Heterocycl Compd 25, 196–197 (1989). https://doi.org/10.1007/BF00479917

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  • DOI: https://doi.org/10.1007/BF00479917

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