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Purines and pyrimidines and condensed systems based on them. 4. Formation of pyrido[6,1-f]xanthines in the reaction of 7-aminotheophylline with ketones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

7-Aminotheophylline reacts with acetone and acetophenone in the presence of anhydrous zinc chloride, forming 1,3,6,8-tetramethyl- and 6,8-dimethyl-1,3-diphenylpyrido[6,1-f]xanthines, respectively. 9-Aminotheophylline gives an analogous reaction product with acetone. The use of acetylacetone affords 4-acetyl-1,3,6,8-tetramethylpyrido[6,1-f]xanthine.

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Literature Cited

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Authors and Affiliations

  1. M. A. Suslov Rostov State University, 344006, Rostov-on-Don

    V. V. Kuz'menko, A. F. Pozharskii, A. I. Chernyshev & I. M. Nanavyan

  2. Scientific-Research Institute of Physical and Organic Chemistry, USSR

    V. V. Kuz'menko, A. F. Pozharskii, A. I. Chernyshev & I. M. Nanavyan

Authors
  1. V. V. Kuz'menko
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  2. A. F. Pozharskii
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  3. A. I. Chernyshev
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  4. I. M. Nanavyan
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Additional information

See [1] for Communication 3.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1551–1554, November, 1987.

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Kuz'menko, V.V., Pozharskii, A.F., Chernyshev, A.I. et al. Purines and pyrimidines and condensed systems based on them. 4. Formation of pyrido[6,1-f]xanthines in the reaction of 7-aminotheophylline with ketones. Chem Heterocycl Compd 23, 1243–1246 (1987). https://doi.org/10.1007/BF00479379

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  • DOI: https://doi.org/10.1007/BF00479379

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