Chemistry of Heterocyclic Compounds

, Volume 24, Issue 8, pp 850–856 | Cite as

Nitrile oxides of the thiophene series: influence of steric factors on stability and reactivity in reactions of 1,3-dipolar cycloaddition

  • M. M. Krayushkin
  • A. A. Loktionov
  • L. I. Belen'kii
Article

Abstract

The synthesis of a series of di- and trialkyl-substituted thiophenecarbonitrile oxides is described. Their addition to styrene is studied together with the quantitative evaluation of the influence of different alkyl groups on the rate of the 1,3-dipolar cycloaddition reaction by the method of competing reactions.

Keywords

Oxide Organic Chemistry Nitrile Styrene Alkyl Group 

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Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • M. M. Krayushkin
    • 1
  • A. A. Loktionov
    • 1
  • L. I. Belen'kii
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryAcademy of Sciences of the USSRMoscow

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