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Chemistry of Heterocyclic Compounds

, Volume 24, Issue 4, pp 413–417 | Cite as

Tetrazoles. 24. Preparation of 1,4-dimethyl- and 2,4-dimethyl-5-aryl-tetrazolium salts

  • I. Yu. Shirobokov
  • M. V. Chekushina
  • V. A. Ostrovskii
  • G. I. Koldobskii
  • G. B. Erusalimskii
Article
  • 38 Downloads

Abstract

Alkylation of 1-methyl-5-aryltetrazoles with dimethyl sulfate leads to the formation of 1,4-dimethyl-5-aryltetrazolium ion salts. Alkylation of isomeric 2-methyl-5-aryltetrazoles also apparently takes place at the N(4) atom. 1-Methyl-5-aryltetrazoles display greater reactivity with respect to methylation than the isomeric 2-methyl-5-aryltetrazoles. 1,4-Dimethyl-5-aryltetrazolium methylsulfate salts isomerize upon heating to give the more stable 2,4-dimethyl-5-aryltetrazolium ion salts.

Keywords

Sulfate Methylation Organic Chemistry Dimethyl Alkylation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • I. Yu. Shirobokov
    • 1
  • M. V. Chekushina
    • 1
  • V. A. Ostrovskii
    • 1
  • G. I. Koldobskii
    • 1
  • G. B. Erusalimskii
    • 1
  1. 1.Lensovet Leningrad Technological InstituteLeningrad

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