Abstract
3,3-Bis(trifluoromethyl)-1-azirine, formed by the reaction of 1-arenesulfonyloxy-2,2-bis(trifluoromethyl)aziridines with nucleophilic reagents, reacts with aliphatic amines with ring-opening and formation of formamidines. With aziridines and diaziridines having a lower electron-donor capability of the nitrogen atom, it forms the adducts -2-aziridino- and -2-diaziridino-3,3-bis(trifluoromethyl)aziridines. All the isomers theoretically possible were recorded for these derivitives by the dynamic NMR method.
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Article 58 of the series “Asymmetric nitrogen.” For Article 57, see [1].
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 472–479, April, 1988.
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Kostyanovskii, R.G., Kadorkina, G.K., Varlamov, S.V. et al. 2-Aziridino- and 2-diaziridino-3,3-bis(trifluoromethyl)aziridines. Chem Heterocycl Compd 24, 387–394 (1988). https://doi.org/10.1007/BF00478856
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DOI: https://doi.org/10.1007/BF00478856