Abstract
2-Propyloxazole (VI) was obtained in a number of steps starting from butyronit rile. The hydrazide and amide were obtained from ethyl 2-propyloxazole-4-carboxylate; the amide was converted to the nitrile, from which the thioamide and amidoxime were obtained by the usual method. Attempts to convert VI to 2-propylisonicotinic acid or its nitrile by the reaction of VI with acrylic acid or acrylonitrile did not give positive results.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 7–9, January, 1972.
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Sycheva, T.P., Pavlova, T.N. & Shchukina, M.N. Synthesis of 2-propyloxazole and 2-propyloxazole-4-carboxylic acid derivatives. Chem Heterocycl Compd 8, 5–7 (1972). https://doi.org/10.1007/BF00478477
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DOI: https://doi.org/10.1007/BF00478477