Chemistry of Heterocyclic Compounds

, Volume 4, Issue 1, pp 110–111 | Cite as

The oxidation of organic compounds

XLIX. The vapor phase catalytic oxidation of tris(hydroxymethyl)-4-picoline
  • T. A. Afanas'eva
  • A. D. Kagarlitskii
  • B. V. Suvorov


In a study of the behavior of tris(hydroxymethyl)-4-picoline (I) under the conditions of vapor-phase oxidation on a vanadium-tin oxide catalyst, it was found that with the addition of 150–250 mole of water and 125–200 mole of O2 per mole of I and a contact time of 0.35–0.45 sec, the main reaction product was isonicotinic acid (II), the yield of which amounted to 60–65% of theoretical, calculated on the I passed.


Oxidation Organic Chemistry Organic Compound Contact Time Hydroxymethyl 
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Copyright information

© The Faraday Press, Inc. 1970

Authors and Affiliations

  • T. A. Afanas'eva
    • 1
  • A. D. Kagarlitskii
    • 1
  • B. V. Suvorov
    • 1
  1. 1.Institute of Chemical SciencesAS Kazakh SSRAlma-Ata

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