Advertisement

Chemistry of Heterocyclic Compounds

, Volume 2, Issue 5, pp 564–567 | Cite as

Researches on the chemistry of heterocyclic systems

XLI. Acidochrome condensation of benzylamides of diarylglycolic acids
  • P. A. Petyunin
  • N. G. Panferova
Article

Abstract

Acidochromic condensation of benzylamides of diarylglycolic acids is used to extend the limits of the method of synthesis of 4, 4-diaryl-3-oxo-1, 2, 3, 4-tetrahydroisoquinolines and the effect of side-chain substituents on heterocyclic ring closure is investigated. The starting benzylamides are synthesized by treating esters of benzyloxamic acids with organomagnesium compounds, and acidochrome condensation of the benzylamides is effected by concentrated sulfuric acid. The UV spectra of the benzylamides and their condensation products have spectroscopic characteristics which closely resemble one another.

Keywords

Ester Organic Chemistry Sulfuric Acid Concentrate Sulfuric Acid Condensation Product 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    P. A. Petyunin, V. S. Shklyaev, and I. S. Berdinskii, ZhOKh, 24, 1078, 1954.Google Scholar
  2. 2.
    P. A. Petyunin and I. S. Berdinskii, ZhOKh, 22, 190, 1952.Google Scholar
  3. 3.
    P. A. Petyunin and V. S. Shklyaev, ZhOKh, 27, 731, 1957.Google Scholar
  4. 4.
    P. A. Petyunin and A. F. Soldatova, KhGS, 261, 1965.Google Scholar
  5. 5.
    P. A. Petyunin and V. S. Shklyaev, ZhOKh, 23, 853, 1953.Google Scholar
  6. 6.
    P. A. Petyunin, ZhOKh, 22, 700, 1952.Google Scholar
  7. 7.
    I. Thiele, Lieb. Ann., 376, 249, 1910.Google Scholar
  8. 8.
    P. A. Petyunin and Z. G. Kalugina, ZhOKh, 33, 2835, 1963.Google Scholar
  9. 9.
    P. A. Petyunin and M. S. Khodyreva, ZhOKh, 33, 755, 1963.Google Scholar
  10. 10.
    H. Freundlich and M. B. Richards, Z. phys. Chem., 79, 181, 1912.Google Scholar
  11. 11.
    S. L. Sapiro, I. M. Rose, and L. Freedman, J. Am. Chem. Soc., 23, 6322, 1959.Google Scholar

Copyright information

© The Faraday Press, Inc. 1968

Authors and Affiliations

  • P. A. Petyunin
    • 1
  • N. G. Panferova
    • 1
  1. 1.Kharkov Pharmaceutical Institute Perm Pharmaceutical InstituteUSSR

Personalised recommendations