Chemistry of Heterocyclic Compounds

, Volume 2, Issue 5, pp 564–567 | Cite as

Researches on the chemistry of heterocyclic systems

XLI. Acidochrome condensation of benzylamides of diarylglycolic acids
  • P. A. Petyunin
  • N. G. Panferova


Acidochromic condensation of benzylamides of diarylglycolic acids is used to extend the limits of the method of synthesis of 4, 4-diaryl-3-oxo-1, 2, 3, 4-tetrahydroisoquinolines and the effect of side-chain substituents on heterocyclic ring closure is investigated. The starting benzylamides are synthesized by treating esters of benzyloxamic acids with organomagnesium compounds, and acidochrome condensation of the benzylamides is effected by concentrated sulfuric acid. The UV spectra of the benzylamides and their condensation products have spectroscopic characteristics which closely resemble one another.


Ester Organic Chemistry Sulfuric Acid Concentrate Sulfuric Acid Condensation Product 
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Copyright information

© The Faraday Press, Inc. 1968

Authors and Affiliations

  • P. A. Petyunin
    • 1
  • N. G. Panferova
    • 1
  1. 1.Kharkov Pharmaceutical Institute Perm Pharmaceutical InstituteUSSR

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