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Investigations in the imidazole series

LIX. Reactions of 2-chloronaphth[1,2-d]imidazole with α-haloketones, β-haloalcohols, olefin oxides, 1,2-dihaloalkanes, and haloacetic acid esters

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Abstract

2-Chloro-3-acylalkyl(β-hydroxyalkyl-, β-haloalkyl-, carbethoxymethyl-, carboxymethyl)-naphth[1,2-d]imidazoles were synthesized by the reaction of 2-chloronaphth[1,2-d]imidazole with α-haloketones, β-haloalcohols, olefin oxides, 1,2-dihaloalkanes, and haloacetic acid esters. The structures of the indicated compounds were established by conversion to the corresponding 3-alkylnaphth[1,2-d]imidazol-2-ones.

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See [1] for communication LVIII.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1115–1120, August, 1971.

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Povstyanoi, M.V., Kochergin, P.M. Investigations in the imidazole series. Chem Heterocycl Compd 7, 1046–1051 (1971). https://doi.org/10.1007/BF00477395

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  • DOI: https://doi.org/10.1007/BF00477395

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