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Delineation of robertsonian translocations in man by means of chromosome banding

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Abstract

Robertsonian translocations from thirteen unrelated individuals were studied by G, Q and C banding, and by autoradiography. Each of three D-D translocations involved chromosomes 13 and 14, all four D-G translocations involved chromosomes 14 and 21, and five of six G-G translocations involved two chromosomes 21 while the sixth involved 21 and 22. Two centromeres were noted in a single 21-21 translocation chromosome by C banding. Autoradiography was much less useful in identifying the chromosomes involved in the thirteen translocations. G and Q banding were consistently accurate.

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Authors and Affiliations

  1. Department of Biology, Memphis State University, 38163, Memphis, Tennessee, USA

    Fontaine S. Hill Jr.

  2. Departments of Pediatrics and Anatomy, University of Tennessee Center for the Health Sciences, 38163, Memphis, Tennessee, USA

    Robert L. Summitt

  3. the Child Development Center, University of Tennessee Center for the Health Sciences, 38163, Memphis, Tennessee, USA

    Robert L. Summitt

Authors
  1. Fontaine S. Hill Jr.
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  2. Robert L. Summitt
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Additional information

Supported in part by Special Project No. 900, Division of Health Services, MCHS, HSMHA, DHEW, and by a grant from the National Foundation-March of Dimes. This work fulfilled in part the requirement of Fontaine S. Hill, Jr. for the Master of Science degree at Memphis State University

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Hill, F.S., Summitt, R.L. Delineation of robertsonian translocations in man by means of chromosome banding. Eur J Pediatr 126, 203–209 (1977). https://doi.org/10.1007/BF00477046

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  • DOI: https://doi.org/10.1007/BF00477046

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