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European Journal of Pediatrics

, Volume 126, Issue 4, pp 203–209 | Cite as

Delineation of robertsonian translocations in man by means of chromosome banding

  • Fontaine S. HillJr.
  • Robert L. Summitt
Original Investigations

Abstract

Robertsonian translocations from thirteen unrelated individuals were studied by G, Q and C banding, and by autoradiography. Each of three D-D translocations involved chromosomes 13 and 14, all four D-G translocations involved chromosomes 14 and 21, and five of six G-G translocations involved two chromosomes 21 while the sixth involved 21 and 22. Two centromeres were noted in a single 21-21 translocation chromosome by C banding. Autoradiography was much less useful in identifying the chromosomes involved in the thirteen translocations. G and Q banding were consistently accurate.

Key words

Chromosomes Chromosome abnormalities Translocation Robertsonian translocation Down's syndrome 13-Trisomy syndrome 

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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • Fontaine S. HillJr.
    • 1
  • Robert L. Summitt
    • 2
    • 3
  1. 1.Department of BiologyMemphis State UniversityMemphisUSA
  2. 2.Departments of Pediatrics and AnatomyUniversity of Tennessee Center for the Health SciencesMemphisUSA
  3. 3.the Child Development CenterUniversity of Tennessee Center for the Health SciencesMemphisUSA

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