Chemistry of Heterocyclic Compounds

, Volume 12, Issue 7, pp 770–775 | Cite as

Synthesis of 2.2,6,6-tetramethylquinucltdines with functional substituents in the quinuclidine ring

  • E. I. Levkoeva
  • L. N. Yakhontov
Article
  • 34 Downloads

Abstract

8-Carboxamido- and 8-phthalimido-2.2,6,6-tetramethylquinuclidines were synthesized. The effect of α,α′-gem-dimethyl groups, which shield the nitrogen atom, on the synthesis of functionally substituted quinuclidine compounds by classical methods was studied.

Keywords

Nitrogen Organic Chemistry Nitrogen Atom Classical Method Quinuclidine 

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Literature cited

  1. 1.
    E. S. Nikits-kaya, I. M. Sharapov, E. I. Levkoeva, V. S. Usovskaya, A. S. Vlasov, T. E. Kukushkina, L. N. Yakhontov, and M. V. Rubtsov, Khim.-Farmats. Zh., No. 10, 58 (1970).Google Scholar
  2. 2.
    E. S. Nikit-skaya, I. M. Sharapov, M. D. Mashkovskii, E. I. Levkoeva, A. S. Vlasov, T. E. Kukushkina, and L. N. Yakhontov, Khim.-Farmats. Zh., No. 8, 59 (1974).Google Scholar
  3. 3.
    L. N. Yakhontov, Usp. Khim., 38, 1038 (1969).Google Scholar
  4. 4.
    G. R. Clemo and T. P. Metcalfe, J. Chem. Soc., 1989 (1937).Google Scholar
  5. 5.
    E. I. Levkoeva, L. N. Yakhontov, and I. M. Sharapov, Khim.-Farmats. Zh., No. 1, 17 (1975).Google Scholar
  6. 6.
    M. V. Rubtsov and M. I. Dorokhova, Zh. Obshch. Khim., 23, 706 (1953).Google Scholar
  7. 7.
    E. Renk and C. A. Grob, Helv, Chim. Acta, 37, 2119 (1954).Google Scholar

Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • E. I. Levkoeva
    • 1
  • L. N. Yakhontov
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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