Abstract
A comparative study was made of the addition of ethanol at the carbonyl group of some 2-formylpyrimidines and aldehydes of other series in which the carbonyl group is activated by the effect of an electron-acceptor grouping (chloral, p-nitrobenzaldehyde, and 2-formylpyridine). It is shown that 2-formylpyrimidines have high reactivities that are comparable with the reactivity of chloral.
Similar content being viewed by others
Literature cited
V. P. Mamaev and M. A. Mikhaleva, Khim. Geterotsikl. Soedin., 535 (1971).
V. P. Mamaev and É. A. Gracheva, Khim. Geterotsikl. Soedin., 1086 (1969).
G. Meadows and B. Darwent, Trans. Faraday Soc., 48, 1015 (1952).
G. Meadows and B. Darwent, Can. J. Chem., 30, 501 (1952).
H. Plieninger and G. Werst, Ber., 89, 2783 (1956).
I. M. Émanuél' and D. G. Knorre, Course in Chemical Kinetics [in Russian], Moscow (1962), p.174.
G. Buthman, Z. Phys. Chem. (B), 23, 100 (1933).
Modern Problems of Physical Organic Chemistry [in Russian], Mir, Moscow (1967), p. 379.
J. W. Baker, Electronic Theories of Organic Chemistry: An Introductory Treatment, Oxford University Press (1958).
W. West (editor), Chemical Application of Spectroscopy, Wiley (1970).
A. R. Katritzky, Physical Methods in Heterocyclic Chemistry, Academic Press (1963).
R. Callighan and M. Wilt, J. Org. Chem., 26, 4913 (1961).
Author information
Authors and Affiliations
Additional information
See [1] for communication XXIX.
Translated from Khimiya Geterotsiklicheskih Soedinenii, No. 6, pp. 838–842, June, 1971.
Rights and permissions
About this article
Cite this article
Mamaev, V.P., Gracheva, É.A. Pyrimidines. Chem Heterocycl Compd 7, 783–786 (1971). https://doi.org/10.1007/BF00476834
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00476834