Advertisement

Chemistry of Heterocyclic Compounds

, Volume 6, Issue 11, pp 1476–1477 | Cite as

Synthesis of 8-trifluoromethylpurines

  • V. M. Cherkasov
  • L. K. Kurilenko
Article

Abstract

The corresponding N4-trifluoromethylpyrimidines, which are cyclized to 8-trifluoromethylpurines at 160–185°C, are obtained by the reaction of N4-substituted 4,5,6-triaminopyrimidines with trifluoroacetic anhydride.

Keywords

Organic Chemistry Anhydride Trifluoroacetic Anhydride 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Literature cited

  1. 1.
    H. C. Koppel and R. K. Robins, J. Org. Chem., 23, 1457 (1958).Google Scholar
  2. 2.
    G. B. Elion, E. Burgi, and G. H. Hitchings, J, Am. Chem. Soc., 73, 5235 (1951).Google Scholar
  3. 3.
    J. Fu, E. Chinoporos, and H. Terzian, J. Org. Chem., 30, 1916 (1965).Google Scholar
  4. 4.
    V. M. Cherkasov and L. K. Kurilenko, Khim. Geterotsikl. Soedin., No. 5, 927 (1968).Google Scholar

Copyright information

© Consultants Bureau 1973

Authors and Affiliations

  • V. M. Cherkasov
    • 1
  • L. K. Kurilenko
    • 1
  1. 1.Institute of Organic ChemistryAcademy of Sciences of the Ukrainian SSRKiev

Personalised recommendations