Chemistry of Heterocyclic Compounds

, Volume 6, Issue 11, pp 1476–1477 | Cite as

Synthesis of 8-trifluoromethylpurines

  • V. M. Cherkasov
  • L. K. Kurilenko


The corresponding N4-trifluoromethylpyrimidines, which are cyclized to 8-trifluoromethylpurines at 160–185°C, are obtained by the reaction of N4-substituted 4,5,6-triaminopyrimidines with trifluoroacetic anhydride.


Organic Chemistry Anhydride Trifluoroacetic Anhydride 
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Literature cited

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Copyright information

© Consultants Bureau 1973

Authors and Affiliations

  • V. M. Cherkasov
    • 1
  • L. K. Kurilenko
    • 1
  1. 1.Institute of Organic ChemistryAcademy of Sciences of the Ukrainian SSRKiev

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